Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins
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Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins
Hsp27 belongs to the heat shock protein family and displays chaperone properties in stress conditions by holding unfolded polypeptides, hence avoiding their inclination to aggregate. Hsp27 is often referenced as an anti-cancer therapeutic target, but apart from its well-described ability to interfere with different stresses and apoptotic processes, its role in non-stressed conditions is still n...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0029719